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The first transcription factor TF known to interact with
2021-04-30

The first transcription factor (TF) known to interact with one of the cis-acting GAREs is GAMYB protein, the expression of which is induced by GA in the aleurone Cy3 NHS ester of barley (HvGAMYB) (Gubler and Jacobsen, 1992). GAMYB is an important regulator of endosperm functions during seed develop
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br Materials and methods br Results
2021-04-30

Materials and methods Results and discussion Acknowledgements This study was supported by the Open Project Program of the Key Laboratory of Mariculture & Enhancement of Zhejiang Province (No. 2016KF003), the Key Project of Zhejiang Province (No. 2016C02055-7), and the International Science
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br Acknowledgments The authors thank Elisabete Lepera and Ro
2021-04-30

Acknowledgments The authors thank Elisabete Lepera and Rosana Silva for technical support. The study was supported by FAPESP, CNPq and PADC/FCF-UNESP. T.T. Miguel was the recipient of a FAPESP (Proc. 05/05171-1) and R.L. Nunes-de-Souza of a CNPq (Proc. 303580/2009-7) fellowship. Introduction
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From materials science it is known that the
2021-04-30

From materials science, it is known that the differences in the annealing temperature is the main factor that mostly influences La (Takai et al., 2003, Cançado et al., 2006). In analogy, controlling the pyrolysis temperature and LOXO-101 during residues burning might be a key aspect to reproduce the
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br Casein Kinase II CK Casein
2021-04-29

Casein Kinase II (CK2) Casein Kinase II (CK2) is a ubiquitous serine/threonine-selective pro-oncogenic protein kinase that has become a more prominent target for research due to its effects and key role in tumorigenesis (Gowda et al., 2017a, Pinna, 2002). CK2, a well-conserved, pleiotropic kinase
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An important focus of the present study
2021-04-29

An important focus of the present study has been the interaction of HUVECs with extracellular matrix in the regulation of angiogenesis. Matrigel is a gelatinous protein extract secreted by Engelbreth–Holm–Swarm mouse sarcoma cells, and is considered to be a good model of the extracellular matrix (Kl
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Imatinib STI is a first line tyrosine kinase inhibitor
2021-04-29

Imatinib (STI-571) is a first-line tyrosine kinase inhibitor (TKI) targeted at breakpoint cluster region-Abelson kinase (ABL) for the treatment of chronic myeloid leukemia (CML) [26]. As a type II inhibitor, imatinib achieves significant selectivity by binding to an inactive DFG-out conformation (DF
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br Materials and Methods br Results
2021-04-29

Materials and Methods Results Discussion Viral infection of eukaryotic HG-10-102-01 activate signaling pathways both via specific interaction with pattern recognition receptors (TLRs, RIG-I, MDA5) and more nonspecific mechanisms such as accumulation of newly synthesized viral glycoproteins
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br Conflict of interest br Acknowledgments and funding We
2021-04-29

Conflict of interest Acknowledgments and funding We thank Jaakko Matomäki, MSc, for the statistical analysis of the data. The study was supported by the Medical Research Council of the Academy of Finland, Decisions no. 250124 and 250114 (Centre of Excellence in Molecular Systems Immunology and
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br Author contribution br Acknowledgements We
2021-04-29

Author contribution Acknowledgements We want to thank Dr. Manuel Rodriguez, Dr. Ch. Blattner, Dr. Jorge Moscat, Dr. Erwin Knecht and Dr. Peter Tontonoz for materials. This work has been supported by grants from the Spanish Ministry of Education and ScienceSAF2011-27442 and a grant from General
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One of the isolated interactors against
2021-04-29

One of the isolated interactors against Mulan259–352–Ube2E3 fusion bait was found to be the GABARAP protein, a known member of the Atg8 family that includes LC3 [20]. The Atg8 family-of-proteins are major players in autophagy/mitophagy since they are part of the autophagosome [20], [21], [22]. Our s
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Expression of DDR in endothelial cells has
2021-04-29

Expression of DDR1 in endothelial cells has been previously described in human corneal blood vessels, and more recently, in murine atherosclerotic plaques (Franco et al., 2008, Mohan et al., 2001). So far, there is a lack of evidence for DDR1 expression in endothelial cells in the mouse blz mg (Fra
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The positive correlation between ATG and DCTPP TCGA data
2021-04-29

The positive correlation between ATG7 and DCTPP1 (TCGA data) suggested our hypothesis that DCTPP1 may affect the phenotype of prostate tumor, or maybe other types of tumors as well, through its role in autophagy. To test this hypothesis, we carried out western-blot experiments in which the ratios of
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Group B phytocystatins are also expressed in caryopses Altho
2021-04-29

Group B phytocystatins are also expressed in caryopses. Although their expression patterns during germination are similar to those of the group A inhibitors, their expression patterns during seed development vary, indicating that they play different roles in the latter process. The highest levels of
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br Conflicts of interest br Acknowledgements br
2021-04-29

Conflicts of interest Acknowledgements Lung cancer continues to be the leading cause of cancer deaths in the US and worldwide., Non–small-cell lung cancer (NSCLC) remains the predominant form of lung cancer (approximately 85%)., With some improvements in surgical techniques and combined ther
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