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br Discussion Intriguingly in a case
2019-04-30
Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite differ
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br CaMKII and heart failure progression
2019-04-30
CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com
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Examples of numerically generated vortices and their
2019-04-30
Examples of numerically generated vortices and their organizing centers in 3-D excitable media are illustrated in Fig. 1. Panels a to d show 4 different configurations of 3-D scroll waves that were computed using the FitzHugh–Nagumo model [39,40]. Panel a shows an example of the simplest configurati
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Cholangiopathies are a group of rare
2019-04-30
Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce
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Desde las organizaciones sociales y poblaciones movilizadas
2019-04-30
Desde las organizaciones sociales y poblaciones movilizadas, estas protestas marcan el inicio de un nuevo periodo de distanciamiento frente Octreotide acetate los actores político-institucionales, en particular el Partido Nacionalista que logró aglutinar electoralmente sus críticas y expectativas de
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br Discussion To our knowledge we report for the first
2019-04-30
Discussion To our knowledge, we report for the first time t(8;21) acute myeloid leukemia presenting as severe aplastic anemia. t(8;21)(q22;q22) is present in 5–10% of all AMLs, and includes variety of subtypes with varying pathology, and clinical presentations, ranging from circulating blast in p
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Cy3 hydrazide br The slow progress in endemicity mapping
2019-04-30
The slow progress in endemicity mapping of neglected tropical diseases (NTDs) in Africa and scaling up of mass drug administration (MDA) in all endemic countries has hampered efforts to meet the London 2020 elimination and control targets. Lymphatic filariasis is targeted to be eliminated by 2020
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In terms of ERS the strongest relationship exists among pati
2019-04-29
In terms of ERS, the strongest relationship exists among patients with Wolff–Parkinson–White syndrome (WPWS) [19–25]. The prevalence of inferolateral early repolarization (ER) pattern has been reported to be approximately 40–50% in patients with WPWS prior to and after catheter ablation [22,23]. Fol
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Ancient schwannoma is usually located deeply
2019-04-29
Ancient schwannoma is usually located deeply in the head and neck, thorax, retroperitoneum, pelvis, and extremities of elderly patients. Spinal canal ancient schwannoma is very rare; there are only few reported cases in the literature. The most common symptom of a spinal schwannoma is pain, either l
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Given that strategies to avoid ONJ are likely
2019-04-29
Given that strategies to avoid ONJ are likely to be more effective than treating the condition once it occurs, it also seems sensible to reduce bisphosphonate exposure as much as possible. This can be accomplished by using less potent agents or less intensive infusion schedules, particularly in thos
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aminolevulinic acid Because complications associated with ac
2019-04-29
Because complications associated with active-fixation atrial leads are related to implantation sites, such as pericardial effusion in patients with the atrial lead implanted in the right atrial free wall and aortic perforation in patients with the implantation site of the mid to high atrial septum [
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Resulta entonces que existe un problema entre el ser
2019-04-29
Resulta, entonces, que existe un problema entre el ser humano y la representación pictórica que de él se hace y que, aun en el caso de la fotografía, siempre se corre el riesgo de que el fotografiado no concuerde con lo que se observa en la impresión. Esas ambivalencias dependen de factores varios,
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It is becoming more evident that chromosomal abnormalities m
2019-04-29
It is becoming more evident that chromosomal abnormalities must act in concert with other genetic lesions to induce overt leukemia. In one of the reported t(7;19) cases an additional submicroscopic deletion near LMO2 was found, which coincided with elevated expression of this gene [8]. In our case w
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When the diagnosis of toxic dystonia and not meningitis was
2019-04-29
When the diagnosis of toxic dystonia, and not meningitis, was suspected, the strategy of investigation changed to a search for a toxic agent causing extrapyramidal reactions. The management of patients with dystonic reactions was modified, lumbar punctures were only performed for those with clear ev
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br Discussion The mechanism of verapamil sensitive
2019-04-28
Discussion The mechanism of verapamil-sensitive ILVT has been suggested as re-entry with an excitable gap and a slow conduction, because the VT can be induced, entrained, and terminated by programmed ventricular or atrial stimulation [1–6]. In addition, previous studies have suggested that the re
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