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Regarding the treatment of HLH with HLH the estimated year
2019-06-11

Regarding the treatment of HLH with HLH-1994, the estimated 3-year probability of survival overall was 55%. According to a previous comprehensive review study, ferritin level may provide a prognostic marker, and regular ferritin measurements may be useful in predicting outcomes in HLH patients. Our
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Even with the limitations in the available data
2019-06-11

Even with the limitations in the available data on DALYs, the funding gap is huge. The Research Investments in Global Health study analysed public and philanthropic infectious disease research awards to UK institutions (1997–2013), and compared them to the burden in DALYs, describing a new metric of
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New ACLS guidelines emphasize the importance of external che
2019-06-11

New ACLS guidelines emphasize the importance of external chest compressions (ECCs), stressing that ECCs should be performed to the correct depth and frequency to guarantee effectiveness [61]. Without gravity, the crewmembers cannot do ECCs in the same way as in a hospital because of Newton\'s third
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Sin embargo no se puede
2019-06-11

Sin embargo, no se puede hablar de etapas delimitadas con absoluta precisión; la revista Simpleton, en 1998, en un artículo que aparece sin firma, apunta que en la década de los veinte no se ignoraba si ganaría la batalla de la prosa americana el adornado estilo de Fitzgerald o la musculosa dicción
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br Tuberculosis remains a global emergency and continues
2019-06-11

Tuberculosis remains a global emergency and continues to present major public health challenges worldwide. The actual global burden of tuberculosis can only be estimated because no accurate data are available from national country programmes from of high tuberculosis endemic countries. The WHO 201
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buy XAV939 A structured inherited arrhythmia or heart diseas
2019-06-11

A structured inherited arrhythmia (or heart disease) clinic provides the platform for optimized multidisciplinary evaluation and management of patients and families with suspected inherited heart disease. The collective efforts of the core staff and access to a variety of experts in related discipli
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br Quantitative analysis The quantitative analysis is based
2019-06-11

Quantitative analysis The quantitative analysis is based on modeling the concentration change of the contrast agent using pharmacokinetic modeling techniques. An initial conversion of SI to concentration values is needed. Concentration vs time curves are then fitted using a bi-compartmental PK mo
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br Adverse events Treatment reported toxicities were similar
2019-06-11

Adverse events Treatment reported toxicities were similar to those previously reported [23]. Discussion Several other studies have addressed the same issue using different bisphosphonates. The SABRE study randomised breast cancer patients taking anastrozole with a T-score of between −1 and −2
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CX-5461 In the largest published case series
2019-06-10

In the largest published case series, Rossi et al. identified seven cases of infant B-ALL, including three cases of congenital leukemia, with lineage switch from B-lymphoid to myelomonocytic leukemia [12]. An additional two cases were described with a switch from AML M5 to B-ALL. Of the nine describ
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This trial included patients who met the ICD
2019-06-10

This trial included 1500 patients, who met the ICD criteria for primary prevention (non-ischemic, ischemic, dual chamber ICD or CRT-D). The patients were randomized to 3 arms: (1) conventional therapy: Zone 1(VT) 170bpm, 2.5s delay, Zone 2 (VF) 200bpm, 1s delay; (2) high rate therapy: Zone 1(VT) 170
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br Discussion The implant of a CRT
2019-06-10

Discussion The implant of a CRT device in a patient with a resting ejection fraction of 50% represents off-guideline use of this therapy [1]. However, since the patient׳s significant NYHA Class III symptoms, LBBB and exertional ventricular dysfunction achieved evidence-based levels for improvemen
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br Conflict of interest br Authors contributions br
2019-06-10

Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in
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br Discussion SIS is a morphological
2019-06-10

Discussion SIS is a morphological characteristic of the basal interventricular septum that protrudes into the LV cavity. This cardiac malformation has generally been considered a natural part of aging without pathophysiological or clinical significance [5,6]. However, several studies demonstrated
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Al frente de esa disputa Jorge Cuesta
2019-06-10

Al frente de esa disputa, Jorge Cuesta mostró que la verdadera tradición mexicana no era nacionalista sino cosmopolita, universal; sin duda, estos poemas de Hora y 20, por lo menos, ayudan purchase congo red comprender la avidez por romper los límites que prevalecía en la mentalidad poética de los C
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El grueso de la poblaci n otavale a de
2019-06-10

El grueso de la población otavaleña de Villanueva lo constituyen parejas jóvenes con niños, indicio de un elevado grado de asentamiento en el contexto de acogida. En oposición al patrón del predominio de varones jóvenes observado por David Kyle en el caso de las migraciones sglt inhibitors Estados U
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